In the pharmaceutical processing and biotech industries, fluid transfer is about far more than moving liquid from A to B — it’s about preserving purity, ensuring process safety, and maintaining regulatory compliance at every stage.
At Action Sealtite, we specialise in providing hose assemblies and couplings designed for high-purity pharmaceutical applications. In this article, we explore the most suitable hose types, coupling options, and essential considerations when specifying components for pharmaceutical fluid transfer.
Compatible Couplings for Pharmaceutical Media
For maintaining cleanability and product integrity, choosing the right connection method is critical. We recommend:
- DryLink® Dry Disconnect Couplings: Ideal for spill-free disconnection in critical environments.
- Hygienic Stainless Steel Couplings: Designed for CIP/SIP cleaning and sterility, perfect for modular pharmaceutical systems.
- Ball Valves & Butterfly Valves: Suitable for control and shut-off in sanitary process lines.
Recommended Hose Types: PTFE and Silicone
PTFE (Polytetrafluoroethylene) Hoses are widely used due to their exceptional chemical resistance, non-stick surface, and ability to handle a wide range of temperatures and pressures. Ideal for aggressive solvents, cleaning fluids, and high-purity media, PTFE hoses are often used in upstream and downstream pharmaceutical production.
Silicone Hoses offer flexibility and are suitable for processes involving sensitive fluids, biological media, and low-pressure applications. They meet FDA, USP Class VI, and BPOG standards for biopharma use.
Key Engineering Considerations
When specifying hose assemblies for pharmaceutical applications, consider the STAMP criteria:
- Size – Inner diameter and wall thickness must match flow demands
- Temperature – Ensure compatibility with both product and cleaning cycles
- Application – Is it transfer, suction, pressure, or steam?
- Media – Know the exact chemical composition of the fluid
- Pressure – Include safety margins for spikes or CIP procedures
In addition to STAMP, it’s essential to evaluate:
- Leachables and extractables: Choose materials with certified low leach rates
- Flow rates and bend radius: To avoid back pressure, and flow disruption
- Spill tolerance: In aseptic environments, containment is critical
Why Choose Action Sealtite?
With decades of experience supporting pharmaceutical manufacturers across the UK, Europe, and the Middle East, we understand the regulatory and operational challenges of your industry. Our product range is backed by technical expertise and reliable customer service.
📞 Call us: +44 (0)1235 512500
📧 Email us: sales@actionsealtite.com